*From the North

(Binghamton) Take RT-7 N/RT-363 E ramp, Merge onto RT-363 E, Merger onto I-81 S/RT-17 E via the ramp to Scranton/New York. Continue to follow 
I-81 S, Take exit 194 for Pennsylvania Turnpike toward US-6/US-11/Clarks Summit.  Keep right at the fork, follow signs for Pennsylvania Turnpike/I-476 S/Allentown and merge onto I-476 S (partial toll road).  Take exit 115 to merge onto PA-315 S toward I81S. Turn left at Mundy Street., Turn left at East End Blvd.

*From the South

(Philadelphia) Head West on Market Street Toward S Juniper Street, Turn right at N Juniper St, Turn Left at John F. Kennedy Blvd. Turn right at Schuylkill Ave, Take ramp onto I-76W.  Take exit 331B to merge onto I-476 toward Plymouth Meeting (Partial Toll Road).  Take exit 105 for PA-115 toward Wilkes-Barre.  Turn left at Bear Creek Blvd/PA-115 Continue to follow PA-115, Continue on PA-309 N. Take exit 1 toward PA-309-BR S/PA-315 N/Wilkes-Barre/Dupont.  Turn right at PA-315 S, Turn left at Mundy Street.  Turn Left at East End Blvd.

*From the East

(Stroudsburg) Head west on Main St/PA-611/US-209-BR toward N 8th Street.  Continue to follow Main St/US-209-BR. Turn right to merge onto I-80 W/US-209 S, Continue to follow I-80 W.  Take exit 277 for NE Extension Turnpike/PA-940/PA-9 toward Lake Harmony.  Keep left at the fork, follow signs for Turnpike/PA-940 W/White Haven/I-476.  Keep right at the fork to continue toward I-476N and merger onto I-476N (Partial Toll Road).  Take Exit 105 for PA-115 N toward Wilkes-Barre.  Turn left at Bear Creek Blvd/PA-115 Continue to follow PA-115.  Continue on PA-309 N.  Take exit 1 toward PA-309-BR S/PA-315 N/Wilkes-Barre/Dupont.  Turn right at PA-315 S, Turn left at Mundy Street.  Turn Left at East End Blvd.

*From the West

(Williamsport) Head northeast on W 3rd Street toward Market Street.  Turn right at market Street, Turn left at US-15 S.  Take the I80 E exit toward Bloomsburg.  Keep left at the fork to continue toward I-80 E and merge onto I-80E.  Take exit 260B on the left to merge onto I-81 N toward Wilkes-Barre.  Take exit 168 Highland Park Blvd toward Wilkes-Barre.  Turn right at Highland Park Blvd.  Turn right at Mundy Street.  Turn right at East End Blvd.