|Sioux Falls VA Health Care System > Driving Directions|
From I-29, take exit 79 to 12th Street. Go east to Kiwanis Avenue. Turn south on Kiwanis Ave. until reaching 22nd St. Turn east on 22nd St. Medical Center & Dakotas Regional Officer are located at 2501 W. 22nd Street. From I-229, take exit 2 and go north on Western Avenue until reaching 22nd Street. Turn west on 22nd Street. Medical Center and Dakotas Regional Office are located at 2501 W. 22nd Street.